1. What is MOTS-c?

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a short 16-amino-acid peptide encoded in the DNA of the mitochondria, the energy-producing structures inside cells. It was first described by researchers in 2015.

2. How does it work?

MOTS-c is studied as a regulator of metabolism. Research suggests it acts on the AMPK pathway, which helps cells manage energy, and it has been investigated for its role in insulin sensitivity, glucose metabolism, exercise capacity and age-related metabolic decline.

3. Research status

MOTS-c is not approved as a medicine. This product is supplied as a sterile lyophilized powder for research purposes only and is not intended for human consumption.